County |
Municipality |
Mile |
# |
Destinations |
Notes |
continues from West Virginia |
Garrett |
Friendsville |
3.8 |
4 |
Maryland Route 42 / Friendsville Road - Friendsville (to U.S. 219) |
trucks for Luke: use  |
|
13.8 |
14 |
  
U.S. 40 west / National Pike / U.S. 219 south / Garrett Highway - Oakland, Addison PA |
south is former route of ; and join  |
Grantsville |
19.2 |
19 |
Maryland Route 495 / Yoder Street-Bittinger Road - Bittinger |
|
|
22.2 |
22 |
  
US 219 north / Chestnut Hill Road - Salisbury PA |
diverges from  |
|
24.0 |
24 |
Lower New Germany Road / Avilton Road - Piney Grove |
|
|
29.8 |
29 |
  
Maryland Route 546 north / Finzel Rd.-Beall School Road - Finzel |
runs north of  |
Allegany |
Frostburg |
33.3 |
33 |
Maryland Route 736 / Midlothian Road-Braddock Rd. - Midlothian |
|
35.0 |
34 |
Maryland Route 36 / New George's Creek Rd. - Frostburg, Westernport (to MD 55) |
|
|
39.2 |
39 |


U.S. 40 Alt west / National Highway / Maryland Route 53 / Winchester Rd. - Frostburg, Cresaptown (to U.S. 220) |
 : westbound entrance/exit only; : eastbound entrance only |
|
39.9 |
40 |
Maryland Route 658 / Campground Rd.-Vocke Rd. - to MD 49 and MD 53 |
No immediate westbound re-entry, traffic must use  WEST. |
|
|
41 |
Seton Drive - to MD 49 |
westbound exit only |
Cumberland |
42.3 |
42 |
  
U.S. 220 south / Greene Street-McMullen Highway, Fletcher Drive - Keyser WV |
Fletcher Drive: eastbound exit and westbound entrance; US 220 has full access; US 220 joins  |
Cumberland/Ridgeley WV |
43.6 |
43A |
Johnson St., Beall St. - to  WV 28 Alt |
Kelly Rd: eastbound entrance only; Johnson St: eastbound access only; Beall St: westbound access only |
Cumberland |
43.9 |
43B-C |
Maryland Route 51 / Industrial Blvd.-Liberty St.-Howard St.-Centre St.-Queen City Dr. - Oldtown |
Howard St: westbound exit only; Centre St: westbound exit only; Liberty St: full westbound access; Queen City Dr: eastbound exit only; Industrial Blvd: eastbound exit only |
44.2 |
43D |
Maryland Avenue |
|
44.9 |
44 |

  
U.S. 40 Alt west / Baltimore Avenue / Maryland Route 639 east / Willowbrook Road - Allegany College of Maryland |
|
|
45.8 |
45 |
  
Maryland Route 952 north / Hillcrest Drive / Columbus Ave. |
: westbound access only; Columbus Ave: eastbound access only |
|
|
|
Maryland Route 807A / Naves Cross Rd. - to MD 144 |
eastbound entrance and exit only |
|
46.5 |
46 |
  
US 220 north / MD 144 / Baltimore Pike - Cumberland Valley PA |
|
|
47.2 |
47 |
Maryland Route 144 / Baltimore Pike-Dehaven Road |
: westbound entrance only, full eastbound access available; Delhaven Rd: westbound entrance only |
|
51.3 |
50 |
Maryland Route 948D / Pleasant Valley Road - Rocky Gap Lodge and Golf Resort (to MD 144) |
|
|
52.5 |
52 |
Maryland Route 144 / Old National Pike-Sunset Orchard Rd. |
westbound exit and eastbound exit |
|
55.6 |
56 |
Maryland Route 144 / Old National Pike-Flintstone Drive - Flintstone |
: eastbound access only; Flintstone Dr: westbound access only |
|
62.9 |
62 |
U.S. 40 Scenic / Fifteen Mile Creek Rd. / Maryland Route 144 / Old National Pike - Green Ridge State Forest |
|
|
64.2 |
64 |
MV Smith Road |
|
|
68.7 |
68 |
Orleans Road - Piney Grove (to U.S. 40 Scenic) |
|
|
71.6 |
72 |
U.S. 40 Scenic / Old National Pike-High Germany Road |
|
Washington |
|
73.6 |
74 |
U.S. 40 Scenic / Old National Pike-High Germany Road-Mountain Road |
westbound and eastbound exit only |
crosses Sideling Hill |
|
77.2 |
77 |
    
U.S. 40 Scenic west / National Pike / Maryland Route 144 east / Western Pike-Woodmont Rd. |
|
Hancock |
81.1 |
82A |
  
U.S. 522 south - Burnt Factory WV |
|
81.1 |
82B |

Interstate 70 east / U.S. 40 east - Hagerstown |
mainline route through interchange |
81.1 |
82C |
  
Interstate 70 west / U.S. 522 north - Breezewood PA |
|
ends at  |