Oleocanthal
From Wikipedia, the free encyclopedia
| Oleocanthal | |
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| Chemical name | (3S,4E)-2-(4-hydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)-4-hexenoate |
| Chemical formula | C17H20O5 |
| Molecular mass | 304.34 g/mol |
| CAS number | [289030-99-5] |
| Density | ? g/cm3 |
| SMILES | OC1=CC=C(CCOC(C[C@H] (CC=O)/C(C=O)=C\C)=O)C=C1 |
| Disclaimer and references | |
Oleocanthal is a natural organic compound isolated from extra virgin olive oil. It is responsible for the slight stinging sensation in the throat when olive oil is consumed.
Oleocanthal has been found to be have anti-inflammatory and antioxidant properties. Similar to classical NSAIDs, it is a non-selective inhibitor of cyclooxygenase (COX). It is suggested that long-term consumption of small quantities of oleocanthal from olive oil may be responsible in part for the low incidence of heart disease associated with a Mediterranean diet.
[edit] References
- "Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil." Beauchamp, Gary K.; Keast, Russell S. J.; Morel, Diane; Lin, Jianming; Pika, Jana; Han, Qiang; Lee, Chi-Ho; Smith, Amos B.; Breslin, Paul A. S. Nature (2005), 437(7055), 45-46.
- "Synthesis and Assignment of Absolute Configuration of (-)-Oleocanthal: A Potent, Naturally Occurring Non-steroidal Anti-inflammatory and Anti-oxidant Agent Derived from Extra Virgin Olive Oils." Smith, Amos B., III; Han, Qiang; Breslin, Paul A. S.; Beauchamp, Gary K. Organic Letters (2005), 7(22), 5075-5078.
