Talk:Orbitofrontal cortex
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[edit] Damage to Orbitofrontal cortex
Doesn't damage to the orbitofrontal cortex also lead to the loss of the sense of smell, and therein most of taste as well? I've read that commonly only the taste for sweet foods is left so that those with Orbitofrontal cortex damage often become obese. I'd add this to the article but can't seem to find a good reference, anybody come across this as well? dr.alf 14:20, 7 November 2006 (UTC)
In frontotemporal dementia there can be over-eating, gluttony, and a tendency to stuff too much food in to the mouth at one time. There may also be changes in food preference for more sweet foods, but FTD is not specific enough to the OFC to say this with any real certainty.
How's about this reference: J. O'Doherty, E. T. Rolls, S. Francis, R. Bowtell, and F. McGlone, Representation of Pleasant and Aversive Taste in the Human Brain, J Neurophysiol 85: 1315-1321, 2001 [1] --PaulWicks 19:16, 7 November 2006 (UTC)
Dr.alf: the loss of the sense of smell (though probably not so much the other phenomena) may be more directly linked to damage to the olfactory bulbs. Because they are located immediately inferior to the orbitofrontal cortex, damage to the olfactory bulbs may frequently accompany orbitofrontal damage. 69.118.25.126 05:27, 12 December 2006 (UTC)
