QAOP keys
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Many games for 8-bit home computers, like the ZX Spectrum, used QAOP as directional control keys.
Left hand was used for vertical movement (Q=up, A=down) while the right hand was used for horizontal movement (O=left, P=right), with the right-hand thumb pressing the space bar or M for 'fire'.
There were also several other sets of keys based on the similar idea. In all cases, the sets were designed to avoid keyboard clash, whereby multiple keys pressed simultaneously would not register if they were within the same input band.
