ROMK
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potassium inwardly-rectifying channel, subfamily J, member 1
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| Identifiers | |
| Symbol | KCNJ1 |
| HUGO | 6255 |
| Entrez | 3758 |
| OMIM | 600359 |
| RefSeq | NM_000220 |
| UniProt | P48048 |
| Other data | |
| Locus | Chr. 11 q24 |
ROMK is an acronym for the Renal Outer Medullary Potassium channel. This is an ATP-dependent potassium channel that transports potassium out of cells.
It plays an important role in potassium recycling in the thick ascending limb (TAL) and potassium secretion in the cortical collecting duct (CCD) of the nephron.
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Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel
Ca: Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm
Na: Sodium channel: SCN4A - SCN5A - SCN9A - Epithelial sodium channel
K: Potassium channel: Voltage-gated (KvLQT1, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain/Resting ion channel
Cl: Chloride channel: Cystic fibrosis transmembrane conductance regulator
Transient receptor potential (TRPV6) - Cyclic nucleotide-gated ion channel - Two-pore channel
