Phenazone

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Phenazone
Systematic (IUPAC) name
1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
Identifiers
CAS number	60-80-0
ATC code	N02BB01
PubChem	2206
Chemical data
Formula	C11H12N2O
Mol. mass	188.226
SMILES	search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Phenazone, or phenazon, is an analgesic. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone is an isomer of phenazine.

Contents 1 Synonyms 2 See also 3 Chimic Class 4 Pharmacology 5 Adverse effects 6 External links

[edit] Synonyms

Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline

[edit] See also

Propyphenazone

[edit] Chimic Class

• Pyrazole
• Pyrazolinone

[edit] Pharmacology

• Analgesics
• Antipyretic
• NSAID

[edit] Adverse effects

• Allergy to pyrazolones
• Nausea
• Agranulocytose

[edit] External links

• Links to external chemical sources

v • d • e Analgesics (N02A, N02B)
Opioids	Bezitramide, Buprenorphine, Butorphanol, Dextromoramide, Dextropropoxyphene, Diamorphine, Dihydrocodeine, Fentanyl, Hydromorphone, Ketobemidone, Methadone, Morphine, Nalbufine, Nicomorphine, Opium, Oxycodone, Papaveretum, Pethidine, Piritramide, Tramadol (see also longer list)
Salicylic acid and derivatives	Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- See also: NSAIDs
Pyrazolones	Aminophenazone, Metamizole, Phenazone
Anilides	Paracetamol (acetaminophen), Phenacetin
Others	Ziconotide, Tetrahydrocannabinol, Ibuprofen, Ketoprofen, Mefenamic Acid, Naproxen, Diclofenac, Flurbiprofen, Diflunisal, Fenoprofen, Indomethacin, Ketorolac, Meclofenamate, Meloxicam, Piroxicam, Tolmetin