User talk:81.104.26.110
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I will find the reference for the potency & duration. The increased duration is because the 7-8 double bond is one point at which the body metabolizes the drug. Potency is a bit harder to explain. The previous version stated it was only 1/2 the potency of morphine. I guess this is from some early German trials on animals that is now discredited. I think I'm right in saying that morphine is not used in Japan, only dihydromorphine because of it's extended duration.
The naming of ketobemidone is wrong. propionoxy would refer to a propionic acid ester when their is a propane-1-one in that position. I might not have got it QUITE right, but it's a lot closer than the current version...
- It wasn't propionoxy, it was propionyl, which is correct. I have now reverted. 213.67.208.25 12:38, 3 November 2006 (UTC)
I have seen it refered to (1 oxo) propane. Is that the old naming convension. I could swear that propionyl refers to an acid substrate (well, when I google it it says so). This is a ketone... Also, couldn't both 4 substituants be refered to as 4 alpha propiophenone?
- Look at the Acetyl article, propionyl is just one extra carbon. And if you don't believe me, look at this scientific article (from 1993!) where they use this exact naming: http://www3.interscience.wiley.com/cgi-bin/abstract/109568002/ABSTRACT?CRETRY=1&SRETRY=0 81.227.124.63 13:24, 5 November 2006 (UTC)
Understood!
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