Etonitazene
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Etonitazene
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| Systematic (IUPAC) name | |
| 2-(p-Ethoxybenzyl)-1-diethylaminoethyl-5-nitrobenzimidazole | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | ? |
| Chemical data | |
| Formula | C22H28N4O3 |
| Mol. mass | 396.48 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Etonitazene is a highly potent narcotic analgesic (1000-1500x morphine). It's the one of several benzimidazole opioids, and is structurally related to clonitazene (where the p-ethoxybenzyl group is replaced by a p-chlorobenzyl group. However, it has only 3x the potency of morphine.).
It has a strong dependency potential similar to that of morphine and therefore is not used in humans. It is, however, useful in addiction studies on animals.
It is the most potent benzimidazole opioid currently known.[1] Other analogues of considerable potency are as follows:
- Methyl (10x morphine)
- Ethyl (30x morphine)
- Propyl (50x morphine)
- Methoxy (100x morphine)
- Isopropoxy (500x morphine)
- Butoxy (200x morphine)
- Methylthio (50x morphine)
- Ethylthio (30x morphine)
These groups replace the p-ethoxy group - there are other possible modifications but these are the most significant.
The drug has proved very important in mapping out the opiate receptor and some experimental compounds in which phenolic groupings have been replaced with nitro groupings have proved more active than the parent compound.[citation needed]
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Acetorphine, Acetyldihydrocodeine, Acetyldihydrocodeinone, Acetylmorphone, Alfentanil, Allylprodine, Alphaprodine, Anileridine, Bemidone, Benzylmorphine, beta-4-morpholinylethylmorphine, Betaprodine, Betmeprodine, Bezitramide, Buprenorphine, Butorphanol, Carfentanil, Clonitazene, Codeine, Codeine-N-Oxide, Codeinone, Cyclazocine, Cyclorphan, Desomorphine, Dextromoramide, Dextropropoxyphene, Dezocine, Diacetyldihydromorphine, Diethylthiambutene, Difenoxin, Dihydrocodeine, Dihydrocodeinone enol acetate, Dihydrohydroxycodeinone, Dihydrodesoxymorphine. Dihydroetorphine, Dihydroheroin, Dihydroisocodeine, Dihydromorphine, Dimethylthiambutene, Diphenoxylate, Dipipanone, Diprenorphine, Dipropanoylmorphine, Ethylketocyclazocine, Ethylmorphine, Etonitazene, Etorphine, Fentanyl, Diamorphine (Heroin), Hydrocodone, Hydromorphone, Isomethadone, Ketobemidone, Laudanum, Lefetamine, Levallorphan, Levo-alphacetylmethadol, Levomethorphan, Levomethadone, Levorphanol, Levopropoxyphene, Loperamide, Meptazinol, Metazocine, Methadone, Metopon, Monoacetylmorphine, Morphine-N-Oxide, Morphine, Morphinone, Morphine-6-glucuronide, MPPP, Myorphine, Nalbuphine, Nalmefene, Nalorphine, Naloxone, Naltrexone, Nicocodeine, Nicodicodeine, Nicomorphine, Norcodeine, N-allyl-normorphine, Ohmefentanyl, Omnopon, Opium, Oxycodone, Oxymorphone, Pantopon, Papaveretum, Paregoric, Pentazocine, PEPAP, Pethidine (Meperidine), Phenadoxone, Phenazocine, Phenoperidine, Pholcodeine, Piminodine, Piritramide, Prodine, Proheptazine, Propiram, Propoxyphene, Racemethorphan, Racemorphan, Remifentanil, Sufentanil, Tetrapon, Thebacon, Thebaine, Thiofentanil, Tilidine, Tramadol, Trimeperidine
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