Flurbiprofen
From Wikipedia, the free encyclopedia
 |
|
|
Flurbiprofen
|
|
| Systematic (IUPAC) name | |
| 2-(3-fluoro-4-phenyl-phenyl)propanoic acid | |
| Identifiers | |
| CAS number | |
| ATC code | M01 M02AA19, S01BC04 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C15H13FO2 |
| Mol. mass | 244.261 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | > 99% |
| Metabolism | Hepatic (CYP2C9) |
| Half life | 4.7-5.7 hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status | |
| Routes | Oral |
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is also known by the trade name ANSAID and marketed by Pfizer.
R-flurbiprofen is the single enantiomer of racemate flurbiprofen; this compound is currently in clinical trials for the treatment of metastatic prostate cancer, and Alzheimer's disease.
Salicylates: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide
Arylalkanoic acids: Diclofenac, Indometacin, Sulindac
2-Arylpropionic acids (profens): Carprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Ketorolac, Loxoprofen, Naproxen, Tiaprofenic acid
N-Arylanthranilic acids (fenamic acids): Mefenamic acid
Pyrazolidine derivatives: Phenylbutazone
Coxibs: Celecoxib, Etoricoxib, Parecoxib, Rofecoxib, Valdecoxib
Sulphonanilides: Nimesulide
Topically used products: Diclofenac, Flurbiprofen, Ibuprofen, Indometacin, Ketoprofen, Naproxen, Piroxicam
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
