Talk:Propofol
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Advantages of propofol include rapid, clear headed recovery within 5-10 minutes, even after prolonged use, and a reduced incidence of postoperative nausea and vomiting.
Is the half-life 30--60 min or 2--24 hr?
- 30-60 min is the elimination phase halflife, as per product information. Initial (re-distribution) phase halflife = 2-4 min. Ld99 11:35, 11 December 2006 (UTC)
Isn't benzyl alcohol toxic? (Or are they only neurotoxic?) Why would it be used as preservatives? I can't say I've seen such formulations yet. Ld99 11:39, 11 December 2006 (UTC)
[edit] Link with Alzheimer's disease
This section is totally absurd. This is the kind of preliminary results that make everyday science, it has not been commented (to my knowledge) and hasn't been extensively scrutinized. It can be then considered as not mainstream knowledge. In a scientific review on propofol, this study will take at most one line, if any. Of note, the journal of publication, Neurochemical Research, is absolutely not notorious. I will therefore remove this section. talk 02:14, 2 January 2007 (UTC)
[edit] Pain on injection
I hestitate to edit such things, but as a nonprofessional I'm going on what the drugs.com website says, who cites the information provided by the drug manufacturer. I presume they know what they're talking about. --Robert Merkel 02:34, 2 January 2007 (UTC)
[edit] Ph-data removal
I have removed the cited pH range for Diprivan as it was incorrect. In fact there are substantial differences between the pH and properties of Diprivan and some of the propofol generics; to explain these would probably fall outside the scope of the article and get into some detailed wrangling over product claims and intellectual property, which is probably not particularly central to the article.
Astrazenece Scientist, 5/1/07 --—The preceding unsigned comment was added by 71.207.34.46 (talk • contribs).
