4-Aminopyridine
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| 4-Aminopyridine | |
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| Chemical name | 4-Aminopyridine |
| Other names | 4-Pyridinamine |
| Chemical formula | C5H6N2 |
| Molecular mass | 94.11 g/mol |
| CAS number | [504-24-5] |
| Melting point | 155-158 °C |
| Boiling point | 273 °C |
| SMILES | NC1=CC=NC=C1 |
| Disclaimer and references | |
4-Aminopyridine or 4-pyridinamine is a potassium channel blocker. It is used primarily as a research tool and is helpful in characterizing subtypes of potassium channels. It has been used clinically in Lambert-Eaton myasthenic syndrome and multiple sclerosis because by blocking potassium channels it prolongs action potentials thereby increasing transmitter release at the neuromuscular junction and elsewhere. The drug, known as Neurelan, has been shown to reverse tetrodotoxin toxicity in animal experiments.[1] It is also marketed as Fampridine by Acorda for the treatment of multiple sclerosis, for which it is now in Phase II clinical trials.
It is also used agriculturally as a non-lethal bird poison.
[edit] See also
[edit] References
- ^ Octopus Envenomations at eMedicine.com
[edit] External links
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