Althesin
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Althesin is an intravenous anaesthetic agent now withdrawn from the market due to severe drug reactions. It was popular because of its short duration of action. It is composed of a mixture of alphaxolone and alphadolone, two steroids. It provides rapid onset of action and recovery.
Cremophor EL was the solubilizing agent (excipient / additive) of Althesin. It should be emphasized that there is no evidence of any toxic action from Cremophor in man. The toxic effects or reactions to Propanidid and Althesin are due to the drugs themselves [1].
[edit] References
- ^ A new Steroid Anaesthetic - Althesin (pdf). PubMed. Retrieved on January 7, 2007. See page 1/49
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