Antistreptolysin O titre
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Antistreptolysin O titre (ASO titre or ASOT) - titre of (serum) antistreptolysin O antibodies; a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci.
The ASOT helps direct the antimicrobial treatment and is used to assist in the diagnosis of scarlet fever, rheumatic fever and post infectious glomeruonephritis.
A positive test usually is >200 units/mL,[1] but normal ranges vary from laboratory to laboratory and by age.[2]
The false negatives rate is 20-30%.[1] If a false negative is suspected then an anti-DNase B titre should be sought. False positives can result from liver disease and tuberculosis.[1]
[edit] References
- ^ a b c Antistreptococcal antibody titres. gpnotebook. URL: http://www.gpnotebook.co.uk/cache/-1630535637.htm. Accessed on: March 31, 2007.
- ^ Danchin M, Carlin J, Devenish W, Nolan T, Carapetis J (2005). "New normal ranges of antistreptolysin O and antideoxyribonuclease B titres for Australian children". J Paediatr Child Health 41 (11): 583-6. PMID 16398843.
[edit] See also
[edit] External links
- Antistreptococcal antibody titres - GPnotebook.co.uk.
- Antistreptolysin O Titer - medterms.com.
- Antistreptolysin O Titer, Serum
- Streptococcal antibody tests - healthAtoZ.com
