Arf6
From Wikipedia, the free encyclopedia
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ADP-ribosylation factor 6
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| Identifiers | |
| Symbol | ARF6 |
| HUGO | 659 |
| Entrez | 382 |
| OMIM | 600464 |
| RefSeq | NM_001663 |
| UniProt | P62330 |
| Other data | |
| Locus | Chr. 14 q21.3 |
ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo. ARF6 has specifically been implicated in endocytosis of plasma membrane proteins and also, to a lesser extent, plasma membrane protein recycling.
ARF6 can interact with ßarrestin upon receptor activation.
[edit] External links
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Heterotrimeric G protein: Transducin
Small GTPase: Ras - Rab (Rab27) - Arf (Arf6) - Ran - Rheb - Rhoa
Elongation factor (Prokaryotic, Eukaryotic)
Dynamin (is a GTPase, is not a G protein)
