Aurora kinase
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Aurora kinases are serine/threonine kinases that are essential for cell proliferation. The enzyme helps the dividing cell share its genetic materials with its daughter cells.
There are three classes of aurora kinases:
- Aurora A (aka Aurora 2) functions during prophase of mitosis and is required for correct function of the centrosomes (the microtubule organising centres in animal cells).
- Aurora B (aka Aurora 1) functions in the attachment of the mitotic spindle to the centromere.
- Aurora C (AURKC) works in germ-line cells and little is known about its function.
[edit] External links
AMP-activated - Aurora (A, B) - Beta adrenergic receptor - Bone morphogenetic protein receptors - c-Raf - Ca2+/calmodulin-dependent (Myosin light-chain) - CDKL5 - Cyclin-dependent - EIF-2 - GSK-3 - Mammalian target of rapamycin - Mitogen-activated/MAP2K/MAP3K (Extracellular signal-regulated, C-Jun N-terminal, P38 mitogen-activated protein) - Phosphorylase - Rhodopsin
Protein kinase A - Protein kinase B - Protein kinase C - Protein kinase G