Bendroflumethiazide

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Bendroflumethiazide
Systematic (IUPAC) name
3-benzyl-5,5-dioxo-9- (trifluoromethyl)-5λ6- thia-2,4-diazabicyclo[4.4.0]deca-7, 9,11-triene-8-sulfonamide
Identifiers
CAS number	73-48-3
ATC code	C03AA01
PubChem	2315
DrugBank	APRD00666
Chemical data
Formula	C15H14F3N3O4S2
Mol. mass	421.417 g/mol
Pharmacokinetic data
Bioavailability	100%
Protein binding	96%
Metabolism	extensive
Half life	3-4 hours[1]
Excretion	?
Therapeutic considerations
Pregnancy cat.	Risk neonatal thrombocytopenia in 3rd trimester[2]
Legal status	POM(UK)
Routes	oral

Bendroflumethiazide INN (formerly BAN bendrofluazide), is a thiazide diuretic, used to treat hypertension.

[edit] Footnotes

1. ^ in Ed. Sean C. Sweetman: Martindale: The complete drug reference, 33, Pharmaceutical Press. 
2. ^ BNF 45 March 2003

[edit] External links

• Links to external chemical sources

v • d • e Antihypertensives (C02) and diuretics (C03)
Antiadrenergic agents (including alpha)	Clonidine, Doxazosin, Guanethidine, Guanfacine, Lofexidine,Mecamylamine, Methyldopa, Moxonidine, Prazosin, Rescinnamine, Reserpine
Vasodilators	Diazoxide, Hydralazine, Minoxidil, Nitroprusside, Phentolamine
Other antihypertensives	Bosentan, Ketanserin
Low ceiling diuretics	Bendroflumethiazide, Chlorothiazide, Chlortalidone, Hydrochlorothiazide, Indapamide, Quinethazone, Mersalyl, Metolazone, Theobromine, Cicletanine
High ceiling diuretics	Bumetanide, Furosemide, Torasemide
Potassium-sparing diuretics	Amiloride, Eplerenone, Spironolactone, Triamterene

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Retrieved from "http://en.wikipedia.org../../../b/e/n/Bendroflumethiazide.html"

Categories: Thiazides | Organic compound stubs | Pharmacology stubs

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• This page was last modified 18:30, 12 February 2007 by Anonymous user(s) of Wikipedia. Based on work by Wikipedia user(s) Davidruben, Fvasconcellos, Beetstra, Arcadian, Benjah-bmm27, Techelf, Bluemoose and Axl.
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