Bisoctrizole
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| Bisoctrizole | |
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| General | |
| Systematic name | 2,2’-Methylene bis-[6-(2H- benzotriazol-2-yl), 4-(1 ,1,3,3- tetramethyl-butyl) phenol] |
| Molecular formula | C41H50N6O2 |
| Molar mass | 658.89 g/mol |
| CAS number | [103597-45-l] |
| Properties | |
| Melting point | 195.7 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references |
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Bisoctrizole (USAN, trade name Tinosorb® M, INCI Methylene Bis-Benzotriazolyl Tetramethylbutylphenol) is a chemical which is added to sunscreens to absorb UV rays. It is a broad spectrum UV absorber, absorbing UVB as well as UVA rays. Bisoctrizole is a hybrid UV absorber. It's made in to small particles (< 200 nm), like microfine zinc oxide and titanium dioxide. And it is organic like most sunscreen actives. It is added to the water phase of a sunscreen as a 50% suspension, while mineral micropigments are usually added to the oil phase.
Bisoctrizole shows very little photodegradation and has a stabilizing effect on other UV absorbers, octyl methoxycinnamate (octinoxate) in particular.
Currently bisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world.
[edit] See also
[edit] External links
http://www.cibasc.com/index/ind-index/ind-per_car/ind-pc-uv/ind-pc-uv-tinosorbm.htm
http://www.dermatologytimes.com/dermatologytimes/article/articleDetail.jsp?id=159652
http://pubs.acs.org/cen/coverstory/83/8315sunscreens.html
http://www.fda.gov/ohrms/dockets/dockets/05n0446/05n-0446-bkg0001-03-Tab-01-vol2.pdf
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