Bronidox
From Wikipedia, the free encyclopedia
Bronidox® (Registered Tradmark of Cognis Corp) is chemical compound 5-Bromo-5-Nitro-1,3-Dioxane. Its use on goods without license from Cognis is strictly prohibited.
- Formula: C4H6BrNO4
- Synonyms:
- 5-Brom-5-Nitro-1,3-Dioxan
- 5-Bromo-5-nitro-m-Dioxan or 5-Bromo-5-nitro-m-Dioxane
- 1,3-Dioxane, 5-Bromo-5-Nitro-
- BRONIDOX® L5
- BRONIDOX® L
- Molecular weight: 212.06.
- Color:
- white crystalline powder
- colourless, transparent liquid in 1,2-propylene glycol
- Melting point: 60 °C [1] or 58.5-62°C [2]
- Light sensitive.
- Solubility: insoluble in water
- pH: 6-7
- Stable under normal conditions
- Non reactive with enzyme/substrate in assays but causes inhibition of enzyme activity n Bacteria [3]
- BRONIDOX® L5 is corrosive on metals [4]
- ??? Incompabilities: strong oxidizing agents ??? [5]
- CAS Number: 30007-47-7
- EINECS Number: 250-001-7
Contents |
[edit] Used as
- Stabilizer
- Surfactant
- It is used in immunology for preserving antibodies and antisera in 0.1 - 0.5% concentration. It is used as preservative to avoid use of sodium azide.
- Bactericide. Very effective against yeast and fungi.
- used in cosmetics since the mid-1970s as preservative for shampoos, foam bath, etc. Maximum concentration is 0.1 %.
[edit] Safety
- Harmful
- Harmful if swallowed R22
- Toxic - tremor, convulsions, excitement
- Irritating to skin R38 - dermatitis
- wear suitable protective clothing S36
- relatively non-toxic to mammals
- some users do not recommend use in preparations destined for in vivo or tissue culture work [6]
- Combustion products: carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen bromide gas, sulphur oxides, hydrogen chloride gas [7]
[edit] Toxicology
according to FSASAX
-
- LD50, rat, ipr. 31 mg/kg 24 hours
[edit] References
- http://www.chemicon.com/webfiles/MSDS/ECM711msds.pdf (Safety data sheet and first aid)
- http://www.chemicalland21.com/lifescience/phar/5-BROMO-5-NITRO-1,3-DIOXANE.htm
- http://www.fitzchem.com/mfg_cogniscare.shtml
- http://www.totalreproduction.com/products/specs/Bronidox.html
- Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox)
- http://www.labodia.com/en/intrinsic_factor/material_safety_data_sheet.pdf
[edit] See also
- Bronopol = 2-Bromo-2-nitropropane-1,3-diol
