Carbamoyl phosphate

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Carbamoyl phosphate
Identifiers
CAS number	[590-55-6]
PubChem	278
MeSH	Carbamoyl+phosphate
Properties
Molecular formula	CH4NO5P
Molar mass	141.020 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Carbamoyl phosphate is an anion of biochemical significance. It is involved In ridding the body of excess nitrogen In the urea cycle, and also in the synthesis of pyrimidines.

It is produced from carbon dioxide, ammonia, and phosphate, the latter derived from from ATP. The synthesis is catalysed by the enzyme carbamoyl phosphate synthase, as follows:

• HCO₃^- + ATP --> ADP + HO-C(O)-OPO₃^-2 (carbonyl phosphate)
• HO-C(O)-OPO₃^-2 + NH₃ + OH^- → HPO₄^2- + ^-O-C(O)NH₂ + H₂O
• ^-O-C(O)NH₂ + ATP → ADP + H₂NC(O)OPO₃^2-

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