Talk:Cat coat genetics
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[edit] comment
Wouldn't it be better to explain the Orange/Black genes with better terms than O and o. The way I learned it was X^O and X^B. That way it showed it was on the X chromosome and that it was incomplete dominance. - not signed
- O and o are the standard terms used among cat breeders. We're not making the terms up, we're reporting them. - Nunh-huh 00:25, 2 Jun 2005 (UTC)
Where does one take that the O gene has incomplete dominance? I was always taught it is completely dominant.Ramdrake 16:48, 12 October 2005 (UTC)
I, too, like the X-superscript system, but I don't like using B vs. O. I see the letter B and think TRP-1. More correctly it should be upper-case and lower case O as the superscript, but given the limitations of the medium, I'll accept O/o. NOT an incomplete dominant but a sex-linked gene. And definitely NOT "the black" gene. They are getting close to finding it, BTW. Not MCR-1 as everyone (including me!) thought, though. Probably Melanocyte Stimulating Hormone, with the wild-type enzyme competing with ASIP on MCR-1, while the mutated form is non-functional --Lorraine
[edit] Freckles
BTW, Where did THIS come from? "Freckles are spots of pigmentation of the underlying sepia color of the cat (see B gene) and can occur on the lips, nose, or ears. The W gene does not prevent freckles or alter eye color, although most cats with this gene have either blue or orange eyes."
First of all "sepia" is a TICA term for a cbcb cat. The B (tyrosine related protein-1) locus is the black/chocolate/cinnamon series. The W gene most definitely is capable of altering eye color through melanocyte apoptosis!!
"Freckles" are simply hyperpigmentation and/or somatic mutation and reversion to wild-type in phaeomelanistic cats (the black spot on the red cat syndrome). In white and white spotted cats, surviving melanocytes can migrate just about anywhere and create a small spot of color. --Lorraine
