Talk:Comet assay
From Wikipedia, the free encyclopedia
Why comet ?
The assay or the name?
The assay is a senstive method to measure DNA damage.
The name comes from the shape of the single cell nucleoid after lysis and electrophoresis. Supercoiled DNA strands when damaged become more "relaxed", therefore travelling as negatively charged strands toward the anode. The more damage, the more DNA is in the "tail of the comet".