Dimethylmercury

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Dimethylmercury

General
Systematic name	Dimethyl mercury
Molecular formula	C₂H₆Hg
Molar mass	230.659 g/mol
Appearance	Colorless liquid
CAS number	[593-74-8]
Properties
Density and phase	2.96 g/ml, liquid
Solubility in water	Insoluble
Melting point	-43 °C
Boiling point	87 - 97 °C
Viscosity	? cP at ?°C
Structure
Molecular shape	?
Hazards
MSDS	External MSDS
Main hazards	?
NFPA 704
Flash point	N/A
R-phrases:	R26, R27, R28, R33, R50, R53
S-phrases:	S13, S28, S36, S45, S60, S61
RTECS number	?
Supplementary data page
Structure and properties	n, ε_r, etc.
Thermodynamic data	Phase behaviour Solid, liquid, gas
Spectral data	UV, IR, NMR, MS
Related compounds
Related compounds	?
Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references

Dimethylmercury ((C H₃)₂Hg) is a flammable, colorless liquid, and one of the strongest known neurotoxins. It is described as having a slightly sweet smell, though inhaling enough fumes to notice this would involve significant exposure to the chemical. It is extremely dangerous, with absorption of doses as low as 0.001 mL being fatal. The high vapor pressure of the liquid means that any spillage will result in dangerous levels of exposure to the fumes for those nearby. Its molecule has a linear structure, with the mercury and carbon atoms in line.

Dimethylmercury crosses the blood-brain barrier easily, probably due to formation of a complex with cysteine. It is eliminated from the organism very slowly, therefore it has tendency to bioaccumulate. The symptoms of poisoning may appear when it is too late for effective treatment.

Dimethylmercury passes through latex, PVC, and neoprene rapidly (within seconds), and is absorbed through the skin. Therefore, most laboratory gloves do not provide adequate protection from it, and the only safe precaution is to handle dimethyl mercury while wearing highly resistant laminated gloves underneath long-cuffed neoprene or other heavy-duty gloves.

The toxicity of dimethylmercury was highlighted when a well-known chemist, Karen Wetterhahn died after spilling a few drops of this compound on her latex-gloved hand.

1 Use
2 See also
3 References
4 External links

[edit] Use

Dimethylmercury is most often used in toxicology experiments as a fixed point of reference due to its extreme toxicity. It has also been used to calibrate NMR instruments for detection of mercury, although less toxic mercury salts are preferred.^[1]^[2]