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Dipipanone

From Wikipedia, the free encyclopedia

Dipipanone
Systematic (IUPAC) name
4,4-Diphenyl-6-(1-piperidinyl)-3-heptanone
Identifiers
CAS number 467-83-4
ATC code  ?
PubChem  ?
Chemical data
Formula C24H31NO 
Mol. mass 349.52
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Dipipanone hydrochloride is an opioid painkiller. In combination with cyclizine hydrochloride, it is marketed as Diconal, indicated for relief of moderate to severe pain.

Chemically, dipipanone belongs to the class of opiates called the 3-diphenyl heptanones. It closely resembles methadone, the only structural difference being the N,N-dimethyl moety of methadone being replaced with a piperidine ring. It's usage is now officially discouraged because of the abuse risk. The combination with cyclizine lends a very strong rush if the drug is injected. During the late 1970s to early 1980s in the UK, a whole spate of deaths were blamed on this preparation. Cyclizine itself was removed from the shelves of pharmacists because opiate addicts were crushing and mixing the drug with street heroin to repliacte the effects.

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