Drugs specifically targeted to treat premature ejaculation
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Premature ejaculation is the most common sexual problem in men affecting 20%-30% of men. It is characterized by a lack of voluntary control over ejaculation.
Studies found that certain antidepressant drugs, such as the group called selective serotonin reuptake inhibitors SSRIs, can also used "off-label" as a treatment for premature ejaculation. They work because one of their positive side effects is to delay ejaculation. One such antidepressant, Hyperforin, one of the principal constituents identified in St John's wort, is being studied to deternmine what positive effects it has on premature ejactualtion (gobbi and Mennini 2001).
To improve the symptoms, the patient should not take these medications on a daily basis to prevent premature ejaculation, just a low dose need to be taken several hours before expected sexual activity.
But experts said that continued SSRI use can have some negative side effects, such as psychiatric problems, weight gain, skin reactions and loss of libido.
Although these medications aren't approved by the Food and Drug Administration (FDA) for the treatment of premature ejaculation, the doctor may recommend sertraline Zoloft, paroxetine Paxil or fluoxetine Prozac, to help delay the ejaculatory process.
Today, research is targeted on revealing and learning the central and peripheral neurological administration mechanism of the ejaculatory process and then regulating it with drugs.
Maybe, Dapoxetine, currently undergoing Phase III clinical evaluation, will be the solution.
[edit] References
- Metz, Michael E. and Barry W. McCarthy. Coping with Premature Ejaculation. Oakland, CA: New Harbinger Publications. 2003.
- Gobbi & T Mennini (October 2001), "Copyright: Is St.John's Wort a 'Prosac-like'herbal antidepressant", Trends Pharmacol Sci 22: 557-559
[edit] Sources
A drug to help premature ejaculation
New drug promises better sex for men
[edit] External links
Categories: Drugs | Andrology | Penis | Sex
