Etidronic acid
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Etidronic acid
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| Systematic (IUPAC) name | |
| (1-hydroxy-1-phosphono-ethyl)phosphonic acid | |
| Identifiers | |
| CAS number | |
| ATC code | M05 M05BB01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C2H8O7P2 |
| Mol. mass | 206.028 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 3% |
| Metabolism | Nil |
| Half life | 1 to 6 hours |
| Excretion | Renal and fecal |
| Therapeutic considerations | |
| Licence data |
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| Pregnancy cat. |
C(US) |
| Legal status |
℞ Prescription only |
| Routes | Oral, intravenous |
Etidronic acid (INN) or etidronate disodium (trade name Didronel®) is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.
[edit] Chelating Agent and Anti-oxidant
Etidronic acid is listed as an ingredient of several cosmetic formulations. Several examples of Etidronic acid's presence in soap products are: Propolis soap, Dove body wash, Yardley of London, Johnson and Johnson's Lavender and Chamomile Creamy Baby Soap bar. Etidronic acid is a chelating agent and may be added to bind or, to some extent, counter the effects of substances, such as arsenic, iron, or other metal ions (that can occur in the presence of some soaps), which may be discharged as a component of grey wastewater and could conceivably contaminate groundwater supplies. Etidronic acid also acts to retard rancidification and oxidation of fatty acids. While etidronic acid has not been limited from inclusion in cosmetics and does have legitimate uses, it is recommended that, as with most cosmetic products (particularly soaps), the product should be thoroughly rinsed from the skin after use.
Nitrogenous: Pamidronic acid, Alendronic acid, Ibandronic acid, Risedronic acid, Zoledronic acid
Non-nitrogenous: Etidronic acid, Clodronic acid, Tiludronic acid
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