Gastrin releasing peptide
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gastrin-releasing peptide
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| Identifiers | |
| Symbol | GRP |
| HUGO | 4605 |
| Entrez | 2922 |
| OMIM | 137260 |
| RefSeq | NM_001012512 |
| UniProt | P07492 |
| Other data | |
| Locus | Chr. 18 q21.1-21.32 |
Gastrin releasing peptide (GRP) is released by the post-ganglionic fibres of the vagus nerve which innervate the G cells of the stomach and stimulate them to release gastrin. GRP is also involved in the biology of the circadian system, playing a role in the signalling of light to the master circadian oscillator in the suprachiasmatic nuclei of the hypothalamus. Furthermore GRP seems to mediate certain aspects of stress.
This is the reason for the observed fact that atropine does not block the vagal effect on gastrin release.
[edit] See also
[edit] External links
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Angiotensin - Bombesin - Bradykinin - Calcitonin - Calcitonin gene-related peptide - Carnosine - Cholecystokinin - Delta sleep-inducing peptide - FMRFamide - Galanin - Gastric inhibitory polypeptide - Gastrin releasing peptide - Gastrin - Motilin - Neuromedin B - Neuropeptide Y - Neurophysins - Neurotensin - Opioid peptide - Pancreatic polypeptide - Pituitary adenylate cyclase activating peptide - Secretin - Tachykinins - Vasoactive intestinal peptide - Vasopressin
Hypothalamic: Somatostatin - CRH - GnRH - GHRH - Orexins - TRH - POMC (ACTH, MSH, Lipotropin)
CCK - EGF - GIP - Gastrin releasing peptide - Gastrins - Proglucagon - Motilin - Peptide YY - Secretin - VIP
