Glucose-1-phosphate
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Glucose-1-phosphate | |
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CAS number | [ | ]
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Molecular formula | C6H13O9P |
Molar mass | 260.136 |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.
It is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell mebrane and so is marked for intracellular catabolism.
Free glucose 1-phosphate can also react with UTP to form UDP-glucose. It can then return to the greater glycogen structure via glycogen synthase.