Protein:HSD11B2
From Wikipedia, the free encyclopedia
|
hydroxysteroid (11-beta) dehydrogenase 2
|
|
| Identifiers | |
| Symbol | HSD11B2 |
| HUGO | 5209 |
| Entrez | 3291 |
| OMIM | 218030 |
| RefSeq | NM_000196 |
| UniProt | P80365 |
| Other data | |
| EC number | 1.1.1.146 |
| Locus | Chr. 16 q22 |
An NAD+-dependent enzyme expressed in aldosterone-selective tissues.
In these tissues, HSD11B2 oxidizes cortisol to cortisone and prevents illicit activation of the mineralocorticoid receptor.
Inhibition of this enzyme results in a condition known as pseudohyperaldosteronism
 |
This enzyme-related article is a stub. You can help Wikipedia by expanding it. |
Carbohydrate dehydrogenases - Lactate dehydrogenase - Malate dehydrogenase - Isocitrate dehydrogenase - Phosphogluconate dehydrogenase - Glucose-6-phosphate dehydrogenase
Hydroxysteroid dehydrogenase: 11 Beta (HSD11B1, HSD11B2) - 3 Beta (3-beta-HSD) - 17 Beta
Glucose oxidase - L-gulonolactone oxidase - Xanthine oxidase
