List of benzodiazepines
From Wikipedia, the free encyclopedia
The various benzodiazepines and their respective trade-names, half-lives, and primary uses are listed in the following table.
 |
The examples and perspective in this article or section may not represent a worldwide view of the subject. Please improve this article or discuss the issue on the talk page. |
 |
The factual accuracy of this section is disputed. Please see the relevant discussion on the talk page |
| Drug Name | Common Brand Names* | Elimination Half-Life (h)** [active metabolite] | Primary Effects | Approximate Equivalent Dose*** |
| Alprazolam | Xanax, Xanor, Tafil, Alprox, Frontal(Brazil) | 6-12 hours | anxiolytic | 0.5 mg |
| Bromazepam | Lexotanil, Lexotan, Lexomil, Somalium, Bromam | 10-20 hours | anxiolytic | 5-6 mg |
| Chlordiazepoxide | Librium, Tropium, Risolid, Klopoxid | 5-30 hours [36-200 hours] | anxiolytic | 25 mg |
| Cinolazepam | Gerodorm | 9 h | sedative | 40 mg |
| Clonazepam | Klonopin, Klonapin, Rivotril | 18-50 hours | anxiolytic, anticonvulsant | 0.5 mg |
| Cloxazolam | Olcadil (Brazil) | 18-50 hours | anxiolytic, anticonvulsant | 1 mg |
| Clorazepate | Tranxene | [36-100 hours] | anxiolytic, anticonvulsant | 15 mg |
| Diazepam | Valium, Apzepam, Stesolid, Vival, Apozepam, Hexalid, Valaxona | 20-100 hours [36-200] | anxiolytic, hypnotic, anticonvulsant, muscle relaxant | 10 mg |
| Estazolam | ProSom | 10-24 h | hypnotic | 1-2 mg |
| Flunitrazepam | Rohypnol, Fluscand, Flunipam, Ronal, Rohydorm (Brazil) | 18-26 hours [36-200 hours] | hypnotic | 1 mg |
| Flurazepam | Dalmadorm, Dalmane | [40-250 hours] | hypnotic | 15-30 mg |
| Halazepam | Paxipam | [30-100 hours] | anxiolytic | 20 mg |
| Ketazolam | Anxon | 2 hours (? Talk) | anxiolytic | 15-30 mg |
| Loprazolam | Dormonoct | 6-12 hours | hypnotic | 1-2 mg |
| Lorazepam | Ativan, Temesta, Lorabenz | 10-20 hours | anxiolytic,anticonvulsant | 1 mg |
| Lormetazepam | Loramet, Noctamid, Pronoctan | 10-12 hours | hypnotic | 1-2 mg |
| Medazepam | Nobrium | 36-200 hours | anxiolytic | 10 mg |
| Midazolam | Dormicum, Versed, Hypnovel, Dormonid (Brazil) | 3 hours (1.8-6 hours) | hypnotic | 5-15 mg |
| Nitrazepam | Mogadon, Apodorm, Pacisyn, Dumolid | 15-38 hours | hypnotic | 5 mg |
| Nordazepam | Madar, Stilny | 50-120 hours | anxiolytic | 10 mg |
| Oxazepam | Seresta, Serax, Serenid, Serepax, Sobril, Oxascand, Alopam, Oxabenz, Oxapax | 4-15 hours | anxiolytic | 25 mg |
| Phenazepam | ||||
| Pinazepam | Domar | [40-100 hours] | sedative | 5-20 mg |
| Prazepam | Centrax | [36-200 hours] | anxiolytic | 10-20 mg |
| Quazepam | Doral | 25-100 hours | hypnotic | 20 mg |
| Temazepam | Restoril, Normison, Euhypnos | 8-22 hours | hypnotic | 15 mg |
| Tetrazepam | Mylostan | 3-26 hours | Skeletal muscle relaxant | 50mg |
| Triazolam | Halcion, Rilamir | 2 hours | hypnotic | 0.25 mg. |
[edit] Atypical benzodiazepine receptor ligands
| Drug Name | Common Brand Names* | Elimination Half-Life (h)** [active metabolite] | Primary Effects | Approximate Equivalent Dose*** |
| Clobazam | Frisium, Urbanol | 8-60 hours | anxiolytic, anticonvulsant | N/A, typical dose 5-20 mg |
| DMCM | ? | ? | anxiogenic, convulsant | N/A, not used therapeutically |
| Flumazenil | Anexate, Lanexat, Mazicon, Romazicon | 1 hour | antidote | N/A, typical dose 0.2 - 0.6 mg |
*Not all trade names are listed. Click on drug name to see a more comprehensive list.
**The duration of apparent action is usually considerably less than the half-life. With most benzodiazepines, noticeable effects usually wear off within a few hours. Nevertheless, as long as the drug is present it will exert subtle effects within the body. These effects may become apparent during continued use or may appear as withdrawal symptoms when dosage is reduced or the drug is stopped.
***Equivalent doses are based on clinical experience but may vary between individuals.[1]
