Rat-bite fever
From Wikipedia, the free encyclopedia
| ICD-10 | A25 |
|---|---|
| ICD-9 | 026 |
Rat-bite fever is an acute, febrile human illness caused by bacteria transmitted by rodents, rats in most cases. Two types of gram-negative facultatively anaerobic bacteria can cause the infection, which is passed from rodent to human via the rodent's urine or mucous secretions.
In rat-bite fever transmitted by the gram-negative rod Streptobacillus moniliformis, symptoms begin to appear two to ten days after a rat bite injury. The illness resembles a severe influenza, with a moderate fever (101-104° F), chills, joint pain, and a diffuse red rash, located mostly on the hands and feet. The causative organism can be isolated by blood culture, and penicillin is the most common treatment. Treatment is usually quite successful, although the body can clear the infection by itself in most cases. Complications are rare, but can include endocarditis and meningitis.
Rat-bite fever transmitted by the gram-negative spirochaete Spirillum minus is more rare, and is found most often in Asia. In Japan the disease is called Sodoku. Symptoms do not manifest for two to four weeks after exposure to the organism, and the wound through which it entered exhibits slow healing and marked inflammation. The fever lasts longer and is recurring, for months in some cases. Joint pain and gastrointestinal symptoms are less severe or are absent. Penicillin is the most common treatment.
Rat-bite fever is known by the alternate names Haverhill Fever and epidemic arthritic erythema.
