Sulfadiazine
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Sulfadiazine
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| Systematic (IUPAC) name | |
| 4-amino-N-pyrimidin-2-yl-benzenesulfonamide | |
| Identifiers | |
| CAS number | |
| ATC code | J01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C10H10N4O2S |
| Mol. mass | 358.146 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
Approved Drug |
| Routes | Cream |
Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).
In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii. This may present in an AIDS patient as multiple ring enhancing lesions on CT. Pregnant women should avoid contact with cat litter which may contain Toxoplasma oocysts.
Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.
[edit] Brand Names
Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid
[edit] See also
[edit] External links
- Sulfadiazine (patient information)
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