Ventral respiratory group
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The ventral respiratory group is a column of neurons extending from caudal facial nucleus to -400μm obex in the medulla and partly responsible for initiation of inspiratory activity. Responsible for motor control of inspiratory and expiratory muscles during excercise. It also contains several neuronal nuclei including the pre-Bötzinger complex, the hypothesized location of central respiratory rhythm pattern generation circuitry. It is currently unclear how this system regulates its output to affect motoneuron bursting, which in turn is responsible for inspiratory muscle innervation.
Research into the function of the pre-Bötzinger complex is currently being studied by making use of the in vitro slice preparation.
[edit] External links
- Dorlands/Elsevier g_12/12403076
- Diagram at colorado.edu
- Overview at vcu.edu
- Original Science Paper on pre-Bötzinger complex
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