Talk:Wallerian degeneration
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The second paragraph seems out of place in this page. "The nerve fiber's neurolemma does not degenerate and remains as a hollow tube. Within 96 hours of the injury, the proximal end of the nerve fiber sends out sprouts towards those tubes and these sprouts are attracted by growth factors produced by Schwann cells in the tubes. If a sprout reaches the tube, it grows into it and advances about 3-4 mm per day, eventually reaching and reinnervating the target tissue. If the sprouts cannot reach the tube, for instance because the gap is too wide or scar tissue has formed, surgery can help to guide the sprouts into the tubes. This regeneration however happens only in peripheral nerves, not in the spinal cord. The crucial difference is that in the central nervous system, including in the spinal chord, myelin sheaths are produced by oligodendrocytes and not by Schwann cells." . The discussion of regeneration in the peripheral and central nervous systems is so general it could be misleading. Sprouting does occur in the CNS in humans and animals and causes compensation after injury. (NeuroHistol 23:16, 8 February 2007 (UTC)).
