High endothelial venules
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High endothelial venules, or HEVs, are a subtype of blood endothelium present within lymph nodes; used by various leukocytes to gain entry into the lymph node via the blood.[1]
The HEVs are made up of cuboidal endothelial cells, with various receptors to allow entry/rolling interactions between leukocytes and the endothelium.
High endothelial venules are found in lymph nodes and tonsils and Peyer's patches, but not in the thymus or spleen.[2]
[edit] References
Bone marrow | Thymus (Hassall's corpuscles) | Spleen (White pulp, Periarteriolar lymphoid sheaths, Marginal zone, Red pulp) | Tonsils/Waldeyer's tonsillar ring (Palatine, Lingual, Adenoid)
Mucosa-associated lymphoid tissue: Gut-associated lymphoid tissue | Peyer's patches
Lymph nodes: Subcapsular sinus | Paracortex | Lymph vessels
Lymph | Lymphocytes | High endothelial venules | Immune system
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