Talk:Insulin resistance
From Wikipedia, the free encyclopedia
I added back the reference to the presentation of Dr. Andrew P. Selwyn on CME on Diabetes that has been deleted during (I suppose) a spamming done a few days ago. This source has been used for the Pathophysiology section. -Eridanis
Why is there an IP number on top of this article? 205.174.22.25 03:36, 6 February 2007 (UTC)
Contents |
[edit] Spam
An anon keeps on inserting an animal study linking bisphenol A with insulin resistance[1]. We have to be very very selective with animal studies. Only if they display a major trend in research, a very useful animal model, or somesuch, are they worthy of inclusion. I agree with Wouterstomp (talk • contribs) this link should stay out until its relevance in humans becomes known. JFW | T@lk 23:35, 18 December 2005 (UTC)
This article is a little heavy for the lay person like myself. Could someone maybe make it a bit more readable for the non medically trained? Pipedreambomb 23:37, 3 March 2006 (UTC)
[edit] Intelligibility
Someone should really re-write that opening sentence in English, no? I think I understand what it's saying, but I'm not confident enough to re-explain it.
...in fact, that goes for much of this article. At the minimum, medical jargon which is likely to be unfamiliar to the educated lay reader should be linked. --Oolong 21:12, 5 June 2006 (UTC)
- I have rewritten the introduction in what I believe is simpler terms and more detail, making wikilinks to all of the medical terms. I hope that this satisfies you. It looks better to me. --Ben Best 14:39, 6 June 2006 (UTC)
[edit] identical to "metabolic syndrome" ?
Since I'm being flamed for edits, I'll just leave the reference, so an approved editor can deal with it:
http://www.ajcn.org/cgi/content/abstract/83/6/1237
The article is heavy. It should also note that there are many causes of insulin resistance including atrophy and cells already being plump with glycogen, autoimmunity is just one, and that both cells and people can be so referred to, since some cells in an individual can be insulin resistant while others aren't.
The essential point is that insulin is a hormone - just the messenger. It requests cells that "excess" glucose be stored as glycogen. If the message isn't acted on, for whatever reason (including not getting to the cell as in autoimmunity), that's "insulin resistance" or at most what parents refer to as "selective hearing." (to be much too flip)
Again, I'm being flamed for contributions, so I will leave this editing task to someone in the inner circle, or much closer to it.
[edit] Monounsaturated Fat-Olive Oil leads to Insulin Resistance? Polyunsaturated Fats All Good?
The one study that I've seen that promotes this hypothesis concerning olive oil is the one this article refers to. There are many more studies that cite olive oil (and other monounsaturated fats)as neutral to good. Additionally, the blanket statement that polyunsaturates (which include omega-6 and omega-3 oils) lessen/mitigate insulin resistance sidesteps the extreme difference in effects of the two on hormone production and inflammation. In essence, the information on fats and insulin resistance appears both biased toward a limited amount of evidence for one hypothesis about monounsaturates(to the exclusion of the greater body of evidence), and a gross generalization that could lead people to believe that all polyunsaturated fats are equal (omega-3's are known to lessen inflammation, while most omega-6's are known for inflammatory properties). I've read that a quarter of the adult population has developed, or is at risk for developing some form of insulin resistance. That's a lot of people who could be coming here for guidance after the doctor has told them they are pre-diabetic, and they deserve better.
-Believe it or not, there are interesting individuals out there (Perricone fans?) who think that fish-based omega-3s reduce inflammation while plant-based omega-3s increase it. I wish I knew where they were getting this.--Dseilhan 21:38, 20 March 2007 (UTC)
