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Talk:List of drugs affected by grapefruit - Wikipedia, the free encyclopedia

Talk:List of drugs affected by grapefruit

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List of drugs affected by grapefruit is part of WikiProject Pharmacology, a project to improve all Pharmacology-related articles. If you would like to help improve this and other pharmacology articles, please join the project. All interested editors are welcome.

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[edit] merge with Grapefruit juice

Grapefruit juice article really is all about drugs and their interaction with grapefruit juice, not anything else about the juice. Gzuckier 21:05, 22 November 2006 (UTC)

I agree, move Grapefruit juice to List of drugs affected by grapefruit. JKW 23:08, 2 January 2007 (UTC)

I'm with Gzukier -- keep this separate. I needed to use this list and I was glad to find it as a discrete article. This is really a pharmacological article -- grapefruit is only chosen because it contains certain chemicals. Notice that orange juice is mentioned at the bottom. Apollo 17:05, 12 January 2007 (UTC)

[edit] Solution to Grapefruit/Grapefruit juice/List of drugs affected by grapefruit

It seems like we have three articles on the same fundamental point - grapefruit juice acts on certain CYP enzymes.

I propose that we eliminate "grapefruit juice" and "list of drugs affected by grapefruit" entirely (redirect to grapefruit), since they revolve entirely around the CYP inhibition effect. Instead of those pages, we can have a brief note in the main grapefruit article about the CYP interactions. That way a reader can follow the link to CYP3A4 or whatever if they want specific information about that.

This way, people who want to know about grapefruits can get relevant information in the article. The article is about grapefruits, not about enzyme/drug interactions - a mere note that it will occur, a brief warning for consumers, and a link to the appropriate articles should suffice. CYP3A4 adequately covers the information expressed in grapefruit juice/list of drugs affected, and does so under a more appropriate title.

Any thoughts, suggestions? My primary concern is that we have multiple articles with the same information, and that we could condense this information and put it into more appropriate articles. 129.170.202.243 07:04, 17 January 2007 (UTC)

I think "List of affected drugs" is a useful article (bias: I initially created this page). I agree that this page and grapefruit juice overlap a lot, however. I think the article about CYP3A4 should discuss the enzyme and its function, and leave its interactions to this page. I will admit that this page isn't very useful if so incomplete. njaard 03:44, 20 January 2007 (UTC)

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