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Lugduname

From Wikipedia, the free encyclopedia

[edit] Lugduname

Currently, Lugduname is the most potent sweetening agent known for humans. Lugduname has been estimated to be between 220,000 & 300,000 times as sweet as sucrose (table sugar), with estimates varying between studies. Lugduname is part of a family of extremely potent, guanidinocarboxylic acid, sweeteners with acetic acid functional groups on guandine.


Lugduname (Zwitterionic form)
Lugduname.bmp
Chemical name N-(4-Cyanophenyl)-N¢-(2,3-methylenedioxybenzyl)guanidinoacetic acid
Chemical formula C18H14N4O4
Molecular mass 352.344 g/mol
SMILES N#Cc1ccc(cc1)N[C+](NCC([O-])=O)NCc2cccc3OCOc23
Disclaimer and references

[edit] References

Jiong Chen, Mookda Pattarawarapan, Alex J. Zhang, and Kevin Burgess. Solution- and Solid-Phase Syntheses of Substituted Guanidinocarboxylic Acids. Journal of Combinatorial Chemistry. (2000) Vol. 2, No. 3 279 (Contains a synthetic method for Lugduname, see Scheme 2)

C. NOFRE, D. GLASER, J. -M. TINTI, and M. WANNER. Gustatory responses of pigs to sixty compounds tasting sweet to humans Journal of Animal Physiology and Animal Nutrition. 86 (2002), pp. 90-96 (Contains the exact structure of Lugdaname)

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