Lugduname
From Wikipedia, the free encyclopedia
[edit] Lugduname
Currently, Lugduname is the most potent sweetening agent known for humans. Lugduname has been estimated to be between 220,000 & 300,000 times as sweet as sucrose (table sugar), with estimates varying between studies. Lugduname is part of a family of extremely potent, guanidinocarboxylic acid, sweeteners with acetic acid functional groups on guandine.
Lugduname (Zwitterionic form) | |
---|---|
Lugduname.bmp | |
Chemical name | N-(4-Cyanophenyl)-N¢-(2,3-methylenedioxybenzyl)guanidinoacetic acid |
Chemical formula | C18H14N4O4 |
Molecular mass | 352.344 g/mol |
SMILES | N#Cc1ccc(cc1)N[C+](NCC([O-])=O)NCc2cccc3OCOc23 |
Disclaimer and references |
[edit] References
Jiong Chen, Mookda Pattarawarapan, Alex J. Zhang, and Kevin Burgess. Solution- and Solid-Phase Syntheses of Substituted Guanidinocarboxylic Acids. Journal of Combinatorial Chemistry. (2000) Vol. 2, No. 3 279 (Contains a synthetic method for Lugduname, see Scheme 2)
C. NOFRE, D. GLASER, J. -M. TINTI, and M. WANNER. Gustatory responses of pigs to sixty compounds tasting sweet to humans Journal of Animal Physiology and Animal Nutrition. 86 (2002), pp. 90-96 (Contains the exact structure of Lugdaname)