Mesuximide
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Mesuximide
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| Systematic (IUPAC) name | |
| 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione | |
| Identifiers | |
| CAS number | |
| ATC code | N03 |
| PubChem | |
| Chemical data | |
| Formula | C12H13NO2 |
| Mol. mass | 203.237 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | Hepatic (demethylation and glucuronidation) |
| Half life | 1.4–2.6 hours (mesuximide) 28–38 hours (active metabolite) |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status | |
| Routes | Oral |
Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin®.[1]
[edit] References
- ^ Pfizer AG (2005). Petinutin® (Mésuximide) (French). Official Pfizer AG Website. Retrieved on August 21, 2006.
Barbiturates: Barbexaclone, Metharbital, Methylphenobarbital, Phenobarbital, Primidone
Hydantoins: Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin
Oxazolidinediones: Ethadione, Paramethadione, Trimethadione
Succinimides: Ethosuximide, Mesuximide, Phensuximide
Benzodiazepines: Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nitrazepam, Temazepam
Carboxamides: Carbamazepine, Oxcarbazepine, Rufinamide Fatty acid derivatives: Valpromide, Valnoctamide
Carboxylic acids: Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine -- GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin
Others:- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine
Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam
Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide
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