Talk:Methemoglobinemia
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[edit] Pictures?
Pictures of people infected with the disease would be a nice addition. Maybe just their hands. Randomfrenchie 01:10, 9 February 2007 (UTC)
[edit] groundwater nitrate
"It can be caused by drinking water nitrate-nitrogen levels that exceed current EPA standards of 10ppm. Nitrate can cause the reaction in the bloodstream, especially in babies."
Actually Methemoglobinemia is caused by drinking water with elevated nitrite-nitrogen levels. Levels of nitrite associated with the reaction have not been documented - levels are transitory. The EPA nitrate criteria is a proxy for dealing with the nitrite concern. Nursing babies are particularly sensitive because their ability to metabolise nitrite is undeveloped. Young children are capable of digesting large quantities of nitrites. The sales of lunch meat and hot dogs relies heavily on this metabolic capacity.- Paleorthid 17:52, 24 January 2006 (UTC)
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- I have found a more informative reference that indicates my previous understanding, as stated above, was simpplistic. Nitrates in water are a problem (in addition to the nitrites) for infants because they metabolize nitrates into nitrites. -- 67.185.75.97 01:24, 5 June 2006 (UTC)
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- The Fugates of Kentucky/West Virginia do not have methemoglobinemia from drinking water, it is a recessive gene carried down in the family. Both parents must carry this gene in order to produce a "blue" child. I know this because I have Fugates in my family lineage and have done research on this family line. There are at least eight generations in my family between the Fugate line and the Ritchie line that have "blue" skin and fingernails. ~~FloraCalifornia
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[edit] Appalachian Blue People
Suggested addition: A very well-known series of cases was among the Moon Family of Eastern Kentucky/Western Virginia area. It carried on through several generations, due to a high amount of intermarriage in the area. This might be an informative addition to the article
- Added, but I saw it was among the Fugate family, per my cited reference. -- Irixman (t) (m) 23:36, 4 June 2006 (UTC)
- I disagree. Do not merge this entry with the entry on the Blue Fugates of Appalachia - continue to provide links and cross-references between the two articles. The Blue Fugate entry has the potential to be expanded as a family history, with many details outside the scope of a general overview of methemoglobinemia. See FloraCalifornia's note above for an example. If more information about the Fugate family is posted to Wikipedia, it would simply clutter up a combined entry, and result in the entries being split apart anyway. -- 71.162.11.76 04:30, 23 November 2006 (UTC)
- I googled 'Blue Fugates' hoping *specifically* to find a Wikipedia entry on them. Since I wrote the above^^^ comment, you have removed all but the most basic information about the Blue Fugates - now there is NO room for the type of biographical information I was looking for, and the Fugates are reduced to a one-paragraph example of symptoms. Can you please explain this decision? -- 71.162.11.76 19:37, 25 November 2006 (UTC)
[edit] Symptoms
I am unsure exactly what the percentages indicates. 70% of people exposed to the LD-50 of any nitrite die? It takes 70% over a normal dose to kill someone? Etc... please readd if anyone knows what they truly indicate, and explain a ibit. -- Irixman (t) (m) 23:36, 4 June 2006 (UTC)