Ofloxacin
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Ofloxacin
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| Systematic (IUPAC) name | |
| (+/-)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)- 7-oxo-7H-pyrido [1,2,3-de]-1, 4-benzoxazine-6-carboxylic acid | |
| Identifiers | |
| CAS number | |
| ATC code | J01 J01MA02, J01MA12, S01AX11, S01AX13, S01AX19, S03AA07 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C18H20FN3O4 |
| Mol. mass | 361.368 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 32% |
| Metabolism | ? |
| Half life | 9 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status | |
| Routes | Topical (ear drops) |
Ofloxacin (sold under the brand name Floxin® in the United States) is a fluoroquinolone antibiotic. Ofloxacin is the racemic mixture of the chiral compound. The biologically active enantiomer is sold separately under the name of levofloxacin. It is used as a treatment for gonorrhoea and is an alternative treatment to ciprofloxacin for anthrax.
[edit] External links
- Ofloxacin: an overview - A site with its chemical properties and alternate brand names.
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| Fluoroquinolones | Ciprofloxacin, Enoxacin, Fleroxacin, Gatifloxacin, Gemifloxacin, Grepafloxacin, Levofloxacin, Lomefloxacin, Moxifloxacin, Norfloxacin, Ofloxacin, Pefloxacin, Prulifloxacin, Rufloxacin, Sparfloxacin, Temafloxacin, Trovafloxacin, Sitafloxacin |
| Other quinolones | Cinoxacin, Flumequine, Nalidixic acid, Oxolinic acid, Pipemidic acid, Piromidic acid, Rosoxacin |
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