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Partial correlation - Wikipedia, the free encyclopedia

Partial correlation

From Wikipedia, the free encyclopedia

In probability theory and statistics, partial correlation measures the degree of association between two random variables, with the effect of a set of controlling random variables removed.

Contents

[edit] Formal definition

Formally, the partial correlation between X and Y given a set of n controlling variables Z = {Z1, Z2, …, Zn}, written ρXY·Z, is the correlation between the residuals RX and RY resulting from the linear regression of X with Z and of Y with Z, respectively.

[edit] Computation

[edit] Using linear regression

The obvious way to compute a (sample) partial correlation is to solve the two associated linear regression problems, get the residuals, and calculate the correlation between the residuals. If we write xi, yi and zi to denote i.i.d. samples of some joint probability distribution over X, Y and Z, solving the linear regression problem amounts to finding

\mathbf{w}_X^* = \arg\min_{\mathbf{w}} \left\{ \sum_{i=1}^N  (x_i - \langle\mathbf{w}, \mathbf{z}_i \rangle)^2 \right\}
\mathbf{w}_Y^* = \arg\min_{\mathbf{w}} \left\{ \sum_{i=1}^N  (y_i - \langle\mathbf{w}, \mathbf{z}_i \rangle)^2 \right\}

with N being the number of samples and \langle\mathbf{v},\mathbf{w} \rangle the scalar product between the vectors v and w. The residuals are then

r_{X,i} = x_i - \langle\mathbf{w}_X^*,\mathbf{z}_i \rangle
r_{Y,i} = y_i - \langle\mathbf{w}_Y^*,\mathbf{z}_i \rangle

and the sample partial correlation is

\hat{\rho}_{XY\cdot\mathbf{Z}}=\frac{N\sum_{i=1}^N r_{X,i}r_{Y,i}-\sum_{i=1}^N r_{X,i}\sum r_{Y,i}} {\sqrt{N\sum_{i=1}^N r_{X,i}^2-\left(\sum_{i=1}^N r_{X,i}\right)^2}~\sqrt{N\sum_{i=1}^N r_{Y,i}^2-\left(\sum_{i=1}^N r_{Y,i}\right)^2}}.

[edit] Using recursive formula

It can be computationally expensive to solve the linear regression problems. Actually, the nth-order partial correlation (i.e., with |Z| = n) can be easily computed from three (n - 1)th-order partial correlations. The zeroth-order partial correlation ρXY·Ø is defined to be the regular correlation coefficient ρXY.

It holds, for any Z_0 \in \mathbf{Z}:

\rho_{XY\cdot \mathbf{Z} } =         \frac{\rho_{XY\cdot\mathbf{Z}\setminus\{Z_0\}} - \rho_{XZ_0\cdot\mathbf{Z}\setminus\{Z_0\}}\rho_{YZ_0\cdot\mathbf{Z}\setminus\{Z_0\}}}              {\sqrt{1-\rho_{XZ_0\cdot\mathbf{Z}\setminus\{Z_0\}}^2} \sqrt{1-\rho_{YZ_0\cdot\mathbf{Z}\setminus\{Z_0\}}^2}}.

Naïvely implementing this computation as a recursive algorithm yields an exponential time complexity. However, this computation has the overlapping subproblems property, such that using dynamic programming or simply caching the results of the recursive calls yields a complexity of \mathcal{O}(n^3).

[edit] Using matrix inversion

Another approach allows to compute in \mathcal{O}(n^3) all partial correlations between any two variables Xi and Xj of a set V of cardinality n given all others, i.e., \mathbf{V} \setminus \{X_i,X_j\}, provided the correlation matrix Ω = (ωij), where ωij = ρXiXj, is invertible. If we define P = Ω-1, we have:

\rho_{X_iX_j\cdot \mathbf{V} \setminus \{X_i,X_j\}} = -\frac{p_{ij}}{\sqrt{p_{ii}p_{jj}}}.

[edit] Interpretation

Geometrical interpretation of partial correlation
Geometrical interpretation of partial correlation

[edit] Geometrical

Let three variables X, Y, Z be chosen from a joint probability distribution over n variables V. Further let vi, 1 ≤ iN, be N n-dimensional i.i.d. samples taken from the joint probability distribution over V. We then consider the N-dimensional vectors x (formed by the successive values of X over the samples), y (formed by the values of Y) and z (formed by the values of Z).

It can be shown that the residuals RX coming from the linear regression of X using Z, if also considered as an N-dimensional vector rX, have a zero scalar product with the vector z generated by Z. This means that the residuals vector lives on a hyperplane Sz which is perpendicular to z.

The same also applies to the residuals RY generating a vector rY. The desired partial correlation is then the cosine of the angle φ between the projections rX and rY of x and y, respectively, onto the hyperplane perpendicular to z.[1]

[edit] As conditional independence test

With the assumption that all involved variables are multivariate Gaussian, the partial correlation ρXY·Z is zero if and only if X is conditionally independent from Y given Z.[2] This property does not hold in the general case.

In order to test if a sample partial correlation \hat{\rho}_{XY\cdot\mathbf{Z}} vanishes, Fisher's z-transform of the partial correlation can be used:

z(\hat{\rho}_{XY\cdot\mathbf{Z}}) = \frac{1}{2} \ln\left(\frac{1+\hat{\rho}_{XY\cdot\mathbf{Z}}}{1-\hat{\rho}_{XY\cdot\mathbf{Z}}}\right).

The null hypothesis is H_0: \hat{\rho}_{XY\cdot\mathbf{Z}} = 0, to be tested against the two-tail alternative H_A: \hat{\rho}_{XY\cdot\mathbf{Z}} \neq 0. We reject H0 with significance level α if:

\sqrt{N - |\mathbf{Z}| - 3}\cdot z(\hat{\rho}_{XY\cdot\mathbf{Z}}) > \Phi^{-1}(1-\alpha/2),

where Φ(·) is the cumulative distribution function of a Gaussian distribution with zero mean and unit standard deviation, and N is the sample size.

[edit] See also

[edit] References

  1. ^ Rummel, R. J. (1976). Understanding Correlation.
  2. ^ Baba, K.; Shibata, R. and Sibuya, M. (2004). "Partial correlation and conditional correlation as measures of conditional independence". Australian and New Zealand Journal of Statistics 46 (4). 

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