Pyridoxine
From Wikipedia, the free encyclopedia
| Pyridoxine | |
|---|---|
 |
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| Common name | pyridoxine |
| Systematic name | 4,5-bis(hydroxymethyl)- 2-methylpyridin-3-ol |
| Other names | 5-hydroxy-6-methyl- 3,4-pyridinedimethanol |
| Chemical formula | C8H11NO3 |
| Molecular mass | 169.18 g/mol |
| Density | x.xxx g/cm3 |
| Melting point | 159-162 °C |
| Boiling point | xx.x °C |
| CAS number | [65-23-6] |
| SMILES | xxxx |
| Disclaimer and references | |
Pyridoxine is one of the compounds that can be called vitamin B6, along with Pyridoxal and Pyridoxamine. It differs from pyridoxamine by the substituent at the '4' position. It is often used as 'pyridoxine hydrochloride'.
Pyridoxine assists in the balancing of sodium and potassium as well as promoting red blood cell production. It is linked to cardiovascular health by decreasing the formation of homocysteine. It has been suggested that Pyridoxine might help children with learning difficulties, and may also prevent dandruff, eczema, and psoriasis.[citation needed] In addition, pyridoxine can help balance hormonal changes in women and aid in immune system. Lack of pyridoxine may cause anemia, nerve damage, seizures, skin problems, and sores in the mouth.[citation needed]
It is based on a pyridine ring, with hydroxyl, methyl, and hydroxymethyl substituents. It is converted to the biologically active form pyridoxal 5-phosphate. It is required for the production of the monoamine neurotransmitters serotonin, dopamine, noradrenaline and adrenaline as it is the cofactor for the enzyme aromatic acid decarboxylase. This enzyme is responsible for converting the precusors 5-hydroxytryptophan (5-htp) into serotonin and 3,4-dihydroxyphenylalanine (l-dopa) into dopamine, noradrenaline and adrenaline. As such it has been implicated in the treatment of depression and anxiety.[citation needed] A very good source of Pyridoxine is dragon fruit from South East Asia. It is given to patients taking Isoniazid to combat the toxic side effects of the drug. Pyridoxine is given 10-50 mg/day to patients on INH (Isoniazid) to prevent Peripheral neuropathy and CNS effects that are associated with the use of isoniazid.
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fat soluble — Retinol (A) | Ergocalciferol and Cholecalciferol (D) | Tocopherol (E) | Naphthoquinone (K)
water soluble — B vitamins (Thiamine (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Pyridoxine (B6), Biotin (B7), Folic acid (B9), Cyanocobalamin (B12)) | Choline | Ascorbic acid (C)
