San Miguel de Gualdape
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San Miguel de Gualdape was a Spanish settlement inside US territory, founded by Lucas Vásquez de Ayllón in 1526. A group of 600 colonists joined Ayllón. The settlement failed in under a year, and all but 150 of the colonists died including Ayllón. The approximate location is the Peedee river area off of the lower Waccamaw river in what is now South Carolina. The first group of African Americans to set foot on what is now the United States were brought by a Spanish explorer to South Carolina to erect the settlement San Miguel de Gualdape, However, they fled to the interior on April 22 and settled with the native American people.