Sialidase
From Wikipedia, the free encyclopedia
Sialidase, accession number PF02973 is a wide-spread enzyme that catalyzes the hydrolysis of terminal acylneuraminic residues from oligosaccharides, glycolipids and glycoproteins. Also called neuraminidase.
It is present as a surface antigen in myxo viruses, hence sialidase inhibitors are used in anti-viral drugs.[1]
Deficiency of this enzyme, an autosomal recessive trait, causes sialidosis; enzyme activity is also lacking in galactosialidosis. The EC nomenclature is exo-α-sialidase.
