Talk:Spirochaete
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[edit] genera of spirochaetes
I believe the information in the spirochaetes article is out of date and that the 3 genera are now known as;
1. Borrelia 2. Leptospira 3. Brachyspira - veterinary species were formally known as Serpulina and before that as Treponema of which T. paracuniculi caused rabbit syphilis
Brachyspira
B. hyodysenteriae causes swine dysentery, a mucohaemorrhagic fibronecrotic colitis causing severe dehydration, loss of condition and death in weaned pigs aged 7 to 20 weeks. Can be seen using Gram stain under a light microscope. It is anaerobic, produces a haemolysin (similar to Streptolysin S) resulting in a complete haemolytic zone on blood agar (used as differential diagnosis from B. innocens a similar but non-pathogenic spiraochaete). Pathogenesis - bacteria colonise colon crypts and invade goblet cells resulting in an overproduction of mucus. Also causes epithelial cell necrosis and erosion. Diarrhoea and dehydration results from impaired ability to absorb water. Disease depend on the presence of other anaerobic or facultative anaerobes
B. pilosicoli is a weakly haemolytic spirochaete. May be the organism responsible for many field cases of spirochaetal diarrhoea or porcine intestinal spirochaetosis. It is a milder form of swine dysentery showing signs of moderate diarrhoea and reduced growth rate.Cdurose 15:10, 9 November 2006 (UTC)