Steven A. Garan

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Steven A. Garan is the director of the Aging Research Centre, and is a leading scientist in the field of aging research. While at the University of California, Berkeley, he played a major role in the invention and the development of the Automated Imaging Microscope System (AIMS). His numerous publications, include articles on systems biology, the effects of caloric restriction on the mouse hypothalamus and on the Automated Imaging Microscope System (AIMS). He is best known for the coining of word "Phenomics", which was defined in an abstract titled: "Phenomics: a new direction for the study of neuroendocrine aging", that was published in the journal Experimental Gerontology, Volume 38 (2003), Issues 1-2, Page 218.

[edit] Publications

• A computational systems biology approach to neuroendocrine aging: Initial results. Experimental Gerontology, Volume 42, Issues 1-2 , January-February 2007, Page 142

• Novel methods in computer-assisted tissue analysis: Customized regional targeting of both cytoplasmic and nuclear-stained tissue. Experimental Gerontology, Volume 42, Issues 1-2 , January-February 2007, Pages 141-142

• Tracking changes in hypothalamic IGF-1 sensitivity with aging and caloric restriction. Experimental Gerontology, Volume 42, Issues 1-2 , January-February 2007, Pages 11-12.

• Insulin-like growth factor-1 receptor immunoreactive cells are selectively maintained in the paraventricular hypothalamus of calorically restricted mice. Int J Dev Neurosci. 2007 Feb;25(1):23-8

• Age-dependent loss of insulin-like growth factor-1 receptor immunoreactive cells in the supraoptic hypothalamus is reduced in calorically restricted mice. Int J Dev Neurosci. 2006 Nov;24(7):431-6.

• A study of insulin-like growth factor-I receptor immunoreactivity in the supraoptic nucleus of young and old female B6D2F1 mice. Experimental Biology, April 2006, 357.5

• Caloric restriction reduces cell loss and maintains estrogen receptor-alpha immunoreactivity in the pre-optic hypothalamus of female B6D2F1 mice, Neuro Endocrinol Lett. 2005 Jun;26(3):197-203.

• A survey of estrogen receptor-alpha immunoreactivity in the hypothalamus of young, old, and old-calorie restricted female B6D2F1 mice, Experimental Gerontology, Volume 39, Issues 11-12, November-December 2004, Page 1771

• Protocal for higher resolution histological images of the mammalian brain, Experimental Gerontology, Volume 39, Issues 11-12, November-December 2004, Page 1770

• Towards a self-learning, self-assembling systemic map of neuroendocrine aging, Experimental Gerontology, Volume 39, Issues 11-12, November-December 2004, Page 1767

• Phenomics: a new direction for the study of neuroendocrine aging. Experimental Gerontology, Volume 38 (2003), Issues 1-2, Page 218

• A comparison of estrogen receptor-alpha immunoreactivity in the arcuate hypothalamus of young and middle-aged C57BL6 female mice. Experimental Gerontology, Volume 38 (2003), Issues 1-2, Page 220

• Creating Three-Dimensional Neuronal Maps of the Mouse Hypothalamus Using an Automated Imaging Microscope System. Experimental Gerontology, Volume 35 numbers 9-10, December 2000, page 1421

• Automated Imaging Microscope System, Linux Journal 2000, Issue 70, Februrary, Page 32-35

[edit] External links

• Aging Research Center: http://www.arclab.org

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• This page was last modified 21:50, 16 March 2007 by Anonymous user(s) of Wikipedia. Based on work by Wikipedia user(s) JBellis, Bluebot, Pufferfish101 and Sgaran.
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