Tropicamide

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Tropicamide
Systematic (IUPAC) name
N-ethyl-3-hydroxy-2-phenyl-N- (pyridin-4-ylmethyl) propanamide
Identifiers
CAS number	1508-75-4
ATC code	S01FA06
PubChem	5593
DrugBank	APRD00287
Chemical data
Formula	C17H20N2O2
Mol. mass	284.353 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	45%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Tropicamide (troe-PIK-a-mide) is an acetylcholine receptor blocker, (a muscarinic antagonist). It is used to dilate (enlarge) the eye's pupil in order to allow better examination of the lens, vitreous humor, and retina. It is typically used during eye examinations, but may also be used before or after eye surgery.

Application of tropicamide can produce short acting mydriasis and cycloplegia.

Tropicamide, a parasympatholytic, is occasionally administered in eye drops in combination with hydroxyamphetamine (brand name Paremyd®), which is a sympathomimetic. The use of drugs stimulating multiple divisions of the autonomic nervous system ensures the dilation the pupil without opposing muscle group firing.

Tropicamide effects on the pupil can last from 6 - 8 hours.

Right eye was instilled by tropicamide, producing anisocoria (unequal pupil size).

Right eye half an hour after administration of tropicamide.

[edit] See also

• Dilated fundus examination

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