Ubiquitin protein ligase E3A
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E3A is an alternative designation of the AWACS platform E-3 Sentry
Ubiquitin protein ligase E3A is an enzyme, in the category called "ubiquitin ligases", that is involved in targeting other proteins to be broken down (degraded) within cells. For example, the p53 protein, which controls cell growth and division, is one of the targets of ubiquitin protein ligase E3A. Protein degradation is a normal process that removes damaged or unnecessary proteins and helps maintain the normal functions of cells.
Ubiquitin protein ligase 3A attaches a small protein called ubiquitin to proteins that should be degraded. Cellular structures called proteasomes recognize and digest proteins tagged with ubiquitin.
UBE3A is the human gene that provides instructions for making ubiquitin protein ligase E3A.
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