Protoporphyrinogen oxidase
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protoporphyrinogen oxidase
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| Identifiers | |
| Symbol | PPOX VP |
| HUGO | 9280 |
| Entrez | 5498 |
| OMIM | 600923 |
| RefSeq | NM_000309 |
| UniProt | P50336 |
| Other data | |
| EC number | 1.3.3.4 |
| Locus | Chr. 1 q22 |
Protoporphyrinogen oxidase (EC 1.3.3.4) is an enzyme that is responsible for the seventh step in heme production. (Heme is the portion of hemoglobin that carries oxygen in the blood from the lungs to the rest of the body.)
Protoporphyrinogen oxidase removes hydrogen atoms from protoporphyrinogen IX (the product of the sixth step in the production of heme) to form protoporphyrin IX.
One additional enzyme must modify protoporphyrin IX before it becomes heme.
[edit] See also
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Ankyrin - Arrestin - Calnexin - Connexin - Dystrophin - Ephrin - Heterotrimeric GTP-binding proteins - LDL-receptor-related protein associated protein - Membrane fusion proteins - Membrane glycoproteins - Membrane transport proteins - Myelin basic protein - Neurofibromin 2 - Phospholipid transfer proteins - Pore forming toxins - Presenilin - Protoporphyrinogen oxidase - Pulmonary surfactant-associated protein B - Pulmonary surfactant-associated protein C - Spectrin - Transmembrane receptors - Utrophin - Vesicular transport proteins
Aminolevulinic acid synthase - Porphobilinogen synthase - Porphobilinogen deaminase - Uroporphyrinogen III synthase - Uroporphyrinogen III decarboxylase - Coproporphyrinogen III oxidase - Protoporphyrinogen oxidase - Ferrochelatase
