Talk:Sphingosine
From Wikipedia, the free encyclopedia
This section says that dehydrosphingosine (usually called 3-ketosphinganine) is enzymatically converted to sphingosine but it isn't. The carbonyl group is reduced, forming dihydrosphingosine (sphinganine), which reacts with a fatty acid-CoA, forming dihydroceramide, which is then dehydrogenated to form the trans double bond at carbons 4 and 5. This is ceramide, which can be hydrolyzed to liberate sphingosine and fatty acid.